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1

Value of Genetic Testing for the Prediction of Long-Term Outcome in Patients With Hypertrophic Cardiomyopathy

van Velzen, Hannah G., Vriesendorp, Pieter A., Oldenburg, Rogier A., van Slegtenhorst, Marjon A., van der Velden, Jolanda, Schinkel, Arend F.L., Michels, Michelle

Journal:

The American Journal of Cardiology

Year:

2016

Language:

english

File:

PDF, 828 KB

english, 2016

2

Clinical Characteristics and Long-Term Outcome of Hypertrophic Cardiomyopathy in Individuals With a MYBPC3 (Myosin-Binding Protein C) Founder MutationCLINICAL PERSPECTIVE

van Velzen, Hannah G., Schinkel, Arend F.L., Oldenburg, Rogier A., van Slegtenhorst, Marjon A., Frohn-Mulder, Ingrid M.E., van der Velden, Jolanda, Michels, Michelle

Journal:

Circulation Cardiovascular Genetics

Year:

2017

Language:

english

File:

PDF, 604 KB

english, 2017

3

Peripartum cardiomyopathy and dilated cardiomyopathy: different at heart

Bollen, Ilse A. E., Van Deel, Elza D., Kuster, Diederik W. D., Van Der Velden, Jolanda

Journal:

Frontiers in Physiology

Year:

2015

Language:

english

File:

PDF, 1.33 MB

english, 2015

4

Hypertrophic cardiomyopathy: a vicious cycle triggered by sarcomere mutations and secondary disease hits

Wijnker, Paul, Sequeira, Vasco, Kuster, Diederik, Velden, Jolanda van der

Journal:

Antioxidants & Redox Signaling

Year:

2018

Language:

english

File:

PDF, 3.16 MB

english, 2018

5

High Fibroblast Growth Factor 23 concentrations in experimental renal failure impair calcium handling in cardiomyocytes

Verkaik, Melissa, Oranje, Maarten, Abdurrachim, Desiree, Goebel, Max, Gam, Zeineb, Prompers, Jeanine J., Helmes, Michiel, ter Wee, Pieter M., van der Velden, Jolanda, Kuster, Diederik W., Vervloet, Ma

Journal:

Physiological Reports

Year:

2018

Language:

english

File:

PDF, 603 KB

english, 2018

6

Untying the knot: protein quality control in inherited cardiomyopathies

Dorsch, Larissa M., Schuldt, Maike, Knežević, Dora, Wiersma, Marit, Kuster, Diederik W. D., van der Velden, Jolanda, Brundel, Bianca J. J. M.

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2018

File:

PDF, 840 KB

2018

7

Untying the knot: protein quality control in inherited cardiomyopathies

Dorsch, Larissa M., Schuldt, Maike, Knežević, Dora, Wiersma, Marit, Kuster, Diederik W. D., van der Velden, Jolanda, Brundel, Bianca J. J. M.

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2018

Language:

english

File:

PDF, 840 KB

english, 2018

8

Cardiac Disorders and Pathophysiology of Sarcomeric Proteins

van der Velden, Jolanda, Stienen, Ger J. M.

Journal:

Physiological Reviews

Year:

2019

Language:

english

File:

PDF, 1.82 MB

english, 2019

9

Mutation-specific pathology and treatment of hypertrophic cardiomyopathy in patients, mouse models and human engineered heart tissue

Wijnker, Paul J.M., van der Velden, Jolanda

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2020

Language:

english

File:

PDF, 4.42 MB

english, 2020

10

Altered myocardial substrate metabolism is associated with myocardial dysfunction in early diabetic cardiomyopathy in rats: studies using positron emission tomography

Charissa E van den Brom, Marc C Huisman, Ronald Vlasblom, Nicky M Boontje, Suzanne Duijst, Mark Lubberink, Carla FM Molthoff, Adriaan A Lammertsma, Jolanda van der Velden, Christa Boer, D Margriet Ouw

Journal:

Cardiovascular Diabetology

Year:

2009

Language:

english

File:

PDF, 1.08 MB

english, 2009

11

How do hypertrophic cardiomyopathy mutations affect myocardial function in carriers with normal wall thickness? Assessment with cardiovascular magnetic resonance

Tjeerd Germans, Iris K Rüssel, Marco JW Götte, Marieke D Spreeuwenberg, Pieter A Doevendans, Yigal M Pinto, Rob J van der Geest, Jolanda van der Velden, Arthur AM Wilde, Albert C van Rossum

Journal:

Journal of Cardiovascular Magnetic Resonance

Year:

2010

Language:

english

File:

PDF, 1.03 MB

english, 2010

12

Increased left ventricular torsion in hypertrophic cardiomyopathy mutation carriers with normal wall thickness

Iris K Rüssel, Wessel P Brouwer, Tjeerd Germans, Paul Knaapen, J Tim Marcus, Jolanda van der Velden, Marco JW Götte, Albert C van Rossum

Journal:

Journal of Cardiovascular Magnetic Resonance

Year:

2011

Language:

english

File:

PDF, 1.32 MB

english, 2011

13

The effect of inhibition of the Na+/H+exchanger on the development of hypertrophy in hypertrophic cardiomyopathy

Wessel P Brouwer, Arjan C Houweling, Marcel G Nederhoff, Tjeerd Germans, Marcel M van Borren, Gerard Pasterkamp, Jolanda van der Velden, Albert C van Rossum

Journal:

Journal of Cardiovascular Magnetic Resonance

Year:

2011

Language:

english

File:

PDF, 186 KB

english, 2011

14

Quantitative analysis of myofilament protein phosphorylation in small cardiac biopsies

Ruud Zaremba, Daphne Merkus, Nazha Hamdani, Jos M. J. Lamers, Walter J. Paulus, Cris dos Remedios, Dirk J. Duncker, Ger J. M. Stienen, Jolanda van der Velden

Journal:

PROTEOMICS - Clinical Applications

Year:

2007

Language:

english

File:

PDF, 331 KB

english, 2007

15

Lack of specificity of antibodies directed against human beta-adrenergic receptors

Nazha Hamdani, Jolanda van der Velden

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2009

Language:

english

File:

PDF, 147 KB

english, 2009

16

Lack of specificity of antibodies directed against human beta-adrenergic receptors

Nazha Hamdani, Jolanda van der Velden

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2009

Language:

english

File:

PDF, 45 KB

english, 2009

17

Protein kinase C α and ε phosphorylation of troponin and myosin binding protein C reduce Ca2+sensitivity in human myocardium

Viola Kooij, Nicky Boontje, Ruud Zaremba, Kornelia Jaquet, Cris dos Remedios, Ger J. M. Stienen, Jolanda van der Velden

Journal:

Basic Research in Cardiology

Year:

2010

Language:

english

File:

PDF, 514 KB

english, 2010

18

Distinct mechanisms for diastolic dysfunction in diabetes mellitus and chronic pressure-overload

Inês Falcão-Pires, Giuseppina Palladini, Nádia Gonçalves, Jolanda van der Velden, Daniel Moreira-Gonçalves, Daniela Miranda-Silva, Francesco Salinaro, Walter J. Paulus, Hans W. M. Niessen, Stefano Per

Journal:

Basic Research in Cardiology

Year:

2011

Language:

english

File:

PDF, 692 KB

english, 2011

19

Diastolic myofilament dysfunction in the failing human heart

Jolanda van der Velden

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2011

Language:

english

File:

PDF, 443 KB

english, 2011

20

Myocardial adaptations in the failing heart: cause or consequence?

Sabine J. van Dijk, Nazha Hamdani, Ger J. M. Stienen, Jolanda van der Velden

Journal:

Journal of Muscle Research and Cell Motility

Year:

2008

Language:

english

File:

PDF, 185 KB

english, 2008

21

A piece of the human heart: variance of protein phosphorylation in left ventricular samples from end-stage primary cardiomyopathy patients

Sabine J. van Dijk, Rozemarije A. Holewijn, Anouk Tebeest, Cris dos Remedios, Ger J. M. Stienen, Jolanda van der Velden

Journal:

Journal of Muscle Research and Cell Motility

Year:

2009

Language:

english

File:

PDF, 254 KB

english, 2009

22

Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium

Paul J. M. Wijnker, Peter Boknik, Ulrich Gergs, Frank U. Müller, Joachim Neumann, Cris dos Remedios, Wilhelm Schmitz, Jürgen R. Sindermann, Ger J. M. Stienen, Jolanda van der Velden, Uwe Kirchhefer

Journal:

Journal of Muscle Research and Cell Motility

Year:

2011

Language:

english

File:

PDF, 557 KB

english, 2011

23

The role of protein kinase C-mediated phosphorylation of sarcomeric proteins in the heart—detrimental or beneficial?

Viola Kooij, Ger J. M. Stienen, Jolanda van der Velden

Journal:

Biophysical Reviews

Year:

2011

Language:

english

File:

PDF, 222 KB

english, 2011

24

The development of familial hypertrophic cardiomyopathy: from mutation to bedside

Wessel P. Brouwer, Sabine J. van Dijk, Ger J. M. Stienen, Albert C. van Rossum, Jolanda van der Velden, Tjeerd Germans

Journal:

European Journal of Clinical Investigation

Year:

2011

Language:

english

File:

PDF, 301 KB

english, 2011

25

Dexrazoxane pre-treatment protects skinned rat cardiac trabeculae against delayed doxorubicin-induced impairment of crossbridge kinetics

Evert L de Beer, Antonio E Bottone, Maartje C van Rijk, Jolanda van der Velden, Emile E Voest

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 193 KB

english, 2002

26

Frequency-dependent myofilament Ca2+ desensitization in failing rat myocardium

Regis R. Lamberts, Nazha Hamdani, Tenoedj W. Soekhoe, Nicky M. Boontje, Ruud Zaremba, Lori A. Walker, Pieter P. De Tombe, Jolanda Van Der Velden, Ger J. M. Stienen

Journal:

The Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 670 KB

english, 2007

27

‘Integrative Physiology 2.0’: integration of systems biology into physiology and its application to cardiovascular homeostasis

Diederik W. D. Kuster, Daphne Merkus, Jolanda van der Velden, Adrie J. M. Verhoeven, Dirk J. Duncker

Journal:

The Journal of Physiology

Year:

2011

Language:

english

File:

PDF, 657 KB

english, 2011

28

Cardiac myosin binding protein C phosphorylation in cardiac disease

Diederik W. D. Kuster, Amira Cholid Bawazeer, Ruud Zaremba, Max Goebel, Nicky M. Boontje, Jolanda van der Velden

Journal:

Journal of Muscle Research and Cell Motility

Year:

2012

Language:

english

File:

PDF, 759 KB

english, 2012

29

Erythropoietin Induces Neovascularization and Improves Cardiac Function in Rats With Heart Failure After Myocardial Infarction

Peter van der Meer, Erik Lipsic, Robert H. Henning, Kristien Boddeus, Jolanda van der Velden, Adriaan A. Voors, Dirk J. van Veldhuisen, Wiek H. van Gilst, Regien G. Schoemaker

Journal:

Journal of the American College of Cardiology

Year:

2005

Language:

english

File:

PDF, 666 KB

english, 2005

30

NOX5 Expression Is Increased in Intramyocardial Blood Vessels and Cardiomyocytes after Acute Myocardial Infarction in Humans

Nynke E. Hahn, Christof Meischl, Tsukasa Kawahara, René J.P. Musters, Viola M.J. Verhoef, Jolanda van der Velden, Alexander B.A. Vonk, Walter J. Paulus, Albert C. van Rossum, Hans W.M. Niessen, Paul A

Journal:

The American Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 1.09 MB

english, 2012

31

Cost-effectiveness and quality of life of granulocyte-colony stimulating factor (filgrastim) after radical vulvectomy and bilateral inguino-femoral lymphadenectomy: results of a randomized clinical trial

Carin A. Uyl-de Groot, Jolanda Gelderblom-den Hartog, Jos G.M. Derksen, Edith A. Symons, Ivonne Buijt, Jacobus van der Velden, Arnold C.M. van Lindert

Journal:

European Journal of Obstetrics & Gynecology and Reproductive Biology

Year:

2004

Language:

english

File:

PDF, 107 KB

english, 2004

32

PKC catalytic subunit and phenylephrine induce a comparable decrease in myofilament calcium sensitivity

Judit Barta, Jolanda van der Velden, Nicky M. Boontje, Ruud Zaremba, Ger J.M. Stienen

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2007

Language:

english

File:

PDF, 53 KB

english, 2007

33

Effect of troponin I Ser23/24 phosphorylation on Ca2+-sensitivity in human myocardium depends on the phosphorylation background

Viola Kooij, Martina Saes, Kornelia Jaquet, Ruud Zaremba, D. Brian Foster, Anne M. Murphy, Cris dos Remedios, Jolanda van der Velden, Ger J.M. Stienen

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2010

Language:

english

File:

PDF, 1.19 MB

english, 2010

34

Why does troponin I have so many phosphorylation sites? Fact and fancy

R. John Solaro, Jolanda van der Velden

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2010

Language:

english

File:

PDF, 377 KB

english, 2010

35

Analysis of cardiac myosin binding protein-C phosphorylation in human heart muscle

O'Neal Copeland, Sakthivel Sadayappan, Andrew E. Messer, Ger J.M. Steinen, Jolanda van der Velden, Steven B. Marston

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2010

Language:

english

File:

PDF, 1.38 MB

english, 2010

36

Exercise training does not improve cardiac function in compensated or decompensated left ventricular hypertrophy induced by aortic stenosis

Elza D. van Deel, Martine de Boer, Diederik W. Kuster, Nicky M. Boontje, Patricia Holemans, Karin R. Sipido, Jolanda van der Velden, Dirk J. Duncker

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2011

Language:

english

File:

PDF, 1.74 MB

english, 2011

37

DISTINCT MECHANISMS FOR DIASTOLIC DYSFUNCTION IN DIABETES MELLITUS AND PRESSURE-OVERLOAD

Ines Pires, Giuseppina Palladini, Nádia Gonçalves, Jolanda van der Velden, Daniel Moreira-Gonçalves, Francesco Salinaro, Walter J. Paulus, Hans WM Niessen, Stefano Perlini, Adelino F. Leite-Moreira

Journal:

Journal of the American College of Cardiology

Year:

2010

Language:

english

File:

PDF, 62 KB

english, 2010

38

THE EFFECT OF INHIBITION OF THE NA+/H+ EXCHANGER ON THE DEVELOPMENT OF HYPERTROPHY IN HYPERTROPHIC CARDIOMYOPATHY

Wessel Brouwer, Arjan C. Houweling, Marcel GJ Nederhoff, Tjeerd Germans, Marcel MGJ van Borren, Gerard Pasterkamp, Jolanda van der Velden, Albert C. van Rossum

Journal:

Journal of the American College of Cardiology

Year:

2011

Language:

english

File:

PDF, 239 KB

english, 2011

39

The HCM-Associated Cardiac Troponin T Mutation K273N in a Human Heart Sample Studied by in Vitro Motility Assay

Bayliss, Christopher, Messer, Andrew, Dos Remedios, Christobal, Van der Velden, Jolanda, Marston, Steven

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

40

The HCM-Associated Cardiac Troponin T Mutation K273N Accelerates Tension Generation and Relaxation in Human Cardiac Myofibrils

Ferrara, Claudia, Piroddi, Nicoletta, Scellini, Beatrice, Ferrantini, Cecilia, van Dijk, Sabine J., dos Remedios, Cris, Tesi, Chiara, van, Jolanda, Velden, der, Poggesi, Corrado

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

41

Perturbed Length-Dependent Activation in Human HCM with Sarcomere Mutations in Thin Filament Proteins

Sequeira, Vasco, Regan, Jessica A., Michels, Michelle, ten Cate, Folkert J., van Slegtenhorst, Marjon A., Stienen, Ger J.M., dos Remedios, Cris, van der Velden, Jolanda

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 55 KB

english, 2012

42

Impact of Site Specific Phosphorylation of the Protein Kinase a Sites Ser23 and Ser24 of Cardiac Troponin I on Contractile Function in Human Cardiomyocytes

Wijnker, Paul J.M., Foster, D. Brian, Coulter, Allison, Frazier, Aisha, Murphy, Anne M., Stienen, Ger J.M., van der Velden, Jolanda

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

43

Reduced Length-Dependent Activation in Human Cardiomyocytes Harboring the Troponin I Mutation R145W

Regan, Jessica, Sequeira, Vasco, Stienen, Ger J.M., Michels, Michelle, ten Cate, Folkert J., van Slegtenhorst, Marjon, dos Remedios, Cris, Konhilas, John, van der Velden, Jolanda

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

44

Posttranslational modifications of cardiac troponin T: An overview

Streng, Alexander S., de Boer, Douwe, van der Velden, Jolanda, van Dieijen-Visser, Marja P., Wodzig, Will K.W.H.

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2013

Language:

english

File:

PDF, 2.11 MB

english, 2013

45

The physiological role of cardiac cytoskeleton and its alterations in heart failure

Sequeira, Vasco, Nijenkamp, Louise L.A.M, Regan, Jessica A., van der Velden, Jolanda

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2014

Language:

english

File:

PDF, 2.00 MB

english, 2014

46

MicroRNA transcriptome profiling in cardiac tissue of hypertrophic cardiomyopathy patients with MYBPC3 mutations

Kuster, Diederik W.D., Mulders, Joyce, ten Cate, Folkert J., Michels, Michelle, dos Remedios, Cristobal G., da Costa Martins, Paula A., van der Velden, Jolanda, Oudejans, Cees B.M.

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

47

Oxidation of Myofilament Protein Sulfhydryl Groups Reduces the Contractile Force and Its Ca 2+ Sensitivity in Human Cardiomyocytes

Hertelendi, Zita, Tóth, Attila, Borbély, Attila, Galajda, Zoltán, van der Velden, Jolanda, Stienen, Ger J.M., Édes, István, Papp, Zoltán

Journal:

Antioxidants & Redox Signaling

Year:

2008

Language:

english

File:

PDF, 238 KB

english, 2008

48

Increased nitrosative/oxidative stress lowers myocardial protein kinase G activity in heart failure with preserved ejection fraction

van Heerebeek, Loek, Hamdani, Nazha, Falcão-Pires, Inês, Leite-Moreira, Adelino F, Begieneman, Mark PV, Bronzwaer, Jean GF, van der Velden, Jolanda, Stienen, Ger JM, Laarman, Gerrit J, Somsen, Aernout

Journal:

BMC Pharmacology and Toxicology

Year:

2013

Language:

english

File:

PDF, 88 KB

english, 2013

49

Impact of Phosphorylation of the Protein Kinase C Sites Ser42/44, Thr143 and Ser199 of Cardiac Troponin I on Myofilament Function in Human Cardiomyocytes

Wijnker, Paul J.M., Foster, D. Brian, Murphy, Anne M., Stienen, Ger J.M., van der Velden, Jolanda

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 41 KB

english, 2013

50

Reduced Maximal Force and Increased Ca2+-Sensitivity of Human Myofilaments Harbouring the HCM-Associated Cardiac Troponin T Mutation K273N

van Dijk, Sabine J., Dooijes, Dennis, dos Remedios, Cris, Stienen, Ger J.M., van der Velden, Jolanda

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 39 KB

english, 2011